London, 1917

When nineteen-year-old Alice Coleman becomes pregnant, she is forced by her father and stepmother to give up the baby. She simply cannot be allowed to bring shame upon her family.  But all Alice can think about is the small, kitten-like child she gave away, and she mourns the father, a young soldier, so beloved, who will never have the chance to know his daughter.

Edith and Philip Burns, a childless couple, yearn for a child of their own. When they secretly adopt a baby girl, Irene, their life together must surely be complete.  Irene grows up knowing that she is different from other children, but no one will tell her the full truth.

Putting hopes of marriage and children behind her, Alice embarks upon a pioneering medical career, striving to make her way in a male-dominated world.  Irene struggles to define her own life, eventually leaving her Suffolk home to find work in London. As two extraordinary stories intertwine across two decades, will secrets long-buried at last come to light?